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Prednisone

Prednisone (Rayos, Prednisone Intensol, Deltasone, Prednisolone and Nycomed are the most common trade names for this active chemical) stands for a medical preparation which referred to the synthetic analogs to cortisone & hydrocortisone – male hormones launched in the adrenal cortex.

Prednisone has the pronounced anti-inflammatory, detoxifying, anti-allergic and antishock actions. It can fight with inflammation as one of incytosolic glucocorticosteroid receptors. Prednisone’s anti-allergic action associated with the reduction of basophils along with inhibition of synthesis of other biologically active substances.

Prednisone: uses and off-label indications

Prednisone is referred to the category of steroid medical preparations assigned for averting the inflammatory processes in a human body.  A therapist may assign Prednisone therapy to people who go through:

  • Ulcerative colitis;
  • Different allergic disorders;
  • Lupus;
  • Any breathing discharges or harsh psoriasis;
  • Arthritis;
  • Skin conditions.

As an off-label medication Prednisone can be also recommended for curing rheumatism, collagen insufficiency, infectious non-specific polyarthritis, acute lymphoblastic leukemia, asthma, infectious mononucleosis, eczema, neurodermatitis & various skin disorders.

Prednisone can also struggle with allergic and chronic conjunctivitis & blepharitis. This drug calms inflammation of the cornea & anterior segment of the eye. In addition, it’s assigned for the therapy of irritated eyeballs associated with injuries & surgeries.

In addition, Prednisone is widely applied in the veterinary practice, for example, it’s terrific for the treatment of atopic dermatitis in cats & dogs.

The major risks to the use of Prednisone

Prednisone’s use may be accompanied with such consequences: hirsutism in women, obesity and acne vulgaris.

In addition, the adverse reaction is the evolvement of mental disorders, reducing the body’s immunity to infections, along with enhanced blood clotting. If you immediately cease the therapy with Prednisone, you may get withdrawal signs leading to an exacerbation of the disorder.

Prednisone is also contraindicated with diabetes mellitus, Cushing’s disorder, acute endocarditis, nephritis, gastric ulcer, osteoporosis & various types of psychoses. It is not advised for pregnant women, elderly patients & people suffering from circulatory insufficiency (stage III), along with those who get lately had surgery, syphilis or active TB.

Immediately cease applying Prednisone if you’ve any of its adverse reactions:

  • Allergic reactions – skin rash, fever, hives, difficulties in breathing;
  • Vision issues;
  • Bloody urine;
  • Upper stomach pains (pancreatis);
  • Weight gain;
  • Low potassium level;
  • High blood pressure degrees;
  • Depressive condition or usual mood changes.

Beware of various side consequences what might be triggered by applying Prednisone. Such factors as drinking alcoholic beverages, weakened immune system, “live” vaccinations & contacts with sick people can enhance the risk of Prednisone’s side consequences. Prednisone can trigger the impairment of usual lab tests and also inform the therapist about the medical preparations that you take on a regular basis. 

Dosage administration to Prednisone

Prednisone is supplied in different forms depending on the used form of the medication– liquid, disintegrating capsules or regular pills. Every form of such medical preparation dictates the individual average dosing that may be adjusted by the therapist in compliance with yours disorder’s nature or other health conditions.

The dosing is established in each case individually. In the acute form of the disorder there are usually assigned 4-6 capsules per day (with 1-2 capsules taken per a single dose). In few cases, like nephrosis, the recommended Prednisone doses must be gradually increased.

Prednisone is usually administered intravenously with the amount of 30-90 mg per day, for curing various disorders – 30-45 mg for the daily dose. In a case of impossibility of injecting the medication into a vein it might be injected deep into the muscle. After the primary relief of the symptoms, continue to apply Prednisone capsules, with the gradual reduction of doses.

How to benefit from applying Prednisone?

Prior to the widespread application of Prednisone, there were no quite a lot of therapies for such severe conditions as skin conditions, bacterial meningitis and severe psoriasis, serious cases of pneumonia, asthma and lupus.

Prednisone is very effective against the severity of the medical condition that needs to be treated. The proved fact is that Prednisone provides multiple health benefits and can be the most effective medication at decreasing the processes of inflammation.